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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GHR
All Species:
13.33
Human Site:
Y226
Identified Species:
29.33
UniProt:
P10912
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10912
NP_000154.1
638
71500
Y226
S
L
K
V
D
K
E
Y
E
V
R
V
R
S
K
Chimpanzee
Pan troglodytes
XP_526938
638
71482
Y226
S
L
K
V
D
K
E
Y
E
V
R
V
R
S
K
Rhesus Macaque
Macaca mulatta
P79194
638
71309
Y226
S
L
K
V
D
K
E
Y
E
V
L
V
R
S
K
Dog
Lupus familis
XP_536502
677
75573
Y254
S
L
Y
P
G
Q
K
Y
L
V
Q
V
R
C
K
Cat
Felis silvestris
Mouse
Mus musculus
P16882
650
72765
H234
S
L
R
M
D
K
E
H
E
V
R
V
R
S
R
Rat
Rattus norvegicus
P16310
638
71218
H226
S
L
R
L
D
K
E
H
E
V
R
V
R
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515848
345
39705
Chicken
Gallus gallus
Q02092
608
68554
F214
T
S
E
K
F
G
E
F
S
E
I
L
Y
V
S
Frog
Xenopus laevis
NP_001081978
603
67604
S218
N
G
K
F
G
E
F
S
D
V
L
H
I
P
L
Zebra Danio
Brachydanio rerio
NP_001077047
570
64111
L196
T
Y
W
E
M
Q
E
L
E
S
G
T
Q
Q
S
Tiger Blowfish
Takifugu rubipres
NP_001072093
510
57234
N136
V
K
P
N
P
P
E
N
V
T
V
L
V
E
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
94.1
24
N.A.
68
69.9
N.A.
30.8
58.6
45.7
35.5
24.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.5
38.8
N.A.
78.9
81
N.A.
38.4
71.3
64.5
51.7
42.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
46.6
N.A.
73.3
73.3
N.A.
0
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
100
100
N.A.
0
33.3
33.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
46
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
0
10
73
0
55
10
0
0
0
10
0
% E
% Phe:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
19
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
10
37
10
0
46
10
0
0
0
0
0
0
0
37
% K
% Leu:
0
55
0
10
0
0
0
10
10
0
19
19
0
0
10
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
10
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
19
0
0
0
0
10
0
10
10
0
% Q
% Arg:
0
0
19
0
0
0
0
0
0
0
37
0
55
0
19
% R
% Ser:
55
10
0
0
0
0
0
10
10
10
0
0
0
46
28
% S
% Thr:
19
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% T
% Val:
10
0
0
28
0
0
0
0
10
64
10
55
10
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
37
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _